Research Activity

Our team is focused on achieving successful outcomes with an evidence-based approach. Dr Broadhead oversees an active research program at the Mid North Coast Hip & Knee Clinic, ensuring that patients benefit from recent advances in the field of musculoskeletal medicine and orthopaedic surgery. Our team has published research widely in peer-reviewed journals and presented internationally.


Peer-Reviewed Publications

  1. Combined autologous chondrocyte implantation (ACI) and mosaicplasty for “Kissing” osteochondral defects of the patellofemoral joint. Sridhar Vijayan, George Bentley. International journal of Orthopaedic Sciences; August 2015; 1(3):06- 08
  2. Long-term results of autologous chondrocyte Implantation in the knee for chronic chondral and osteochondral defects. Leela C Biant, George Bentley, Sridhar Vijayan, John A Skinner, Richard WJ Carrington. American Journal of Sports Medicine; September 2014; 42 (pages 2178-2183) PMID: 25002462
  3. Revision cartilage cell transplantation for failed autologous chondrocyte transplantation in chronic osteochondral defects of the knee. Sridhar Vijayan, George Bentley, Jeeshan Rahman, Timothy WR Briggs, John A Skinner, Richard WJ Carrington. Bone And Joint Journal (Br); January 2014: 96-B (pages 54-58) PMID: 24395311
  4. Autologous chondrocyte Implantation (ACI) for osteochondral lesions in the knee using a bilayer collagen membrane and bone graft: a 2-8 year follow-up study. Sridhar Vijayan, William Bartlett, George Bentley, Richard WJ Carrington, John A Skinner, Robin C Pollock, Mohammed Alorjani, Timothy WR Briggs. Journal of Bone and 488-492) PMID: 22434464
  5. Minimum ten year results of a prospective randomised study of Autologous Chondrocyte Implantation versus Cartilage Lesions of the Knee. George Bentley, Leela C Biant, Sridhar Vijayan, Simon Macmull, John A Skinner, Richard WJ Carrington. Journal of Bone and Joint Surgery (Br); April 2012: 94-B (pages 504- 509) PMID: 22434467
  6. Normocalcaemic Tetany. Vinay Sehgal, Sridhar Vijayan, Shahena Yasmin, U Srirangalingam, J Pati, William M Drake. 11 No 6 (pages 594-595) PMID: 22268317
  7. The Stanmore Knee Arthrodesis Prosthesis. William Bartlett, Sridhar Vijayan, Robin Pollock, John A Skinner, Gordon Blunn, Steve R Cannon, Timothy WR Briggs. The Journal of Arthroplasty September 2011: Volume 26 Issue 6 (pages 903- 908) PMID: 21074358
  8. Combined Autologous Chondrocyte Implantation (ACI) with supra-condylar femoral varus osteotomy, following lateral growth-plate damage in the adolescent knee; 8-year follow-up. Sridhar Vijayan, George Bentley. Sports Medicine, Technology; March 2011: 3:5 PMID: 21418566
  9. Use Of Irradiated autologous bone in joint sparing endoprosthetic femoral William Bartlett, Robert Lee, Peter Ostler, Gordon W Blunn, Stephen R Cannon, Timothy WR Briggs. Indian Journal of Orthopaedics; March 2011: Volume 45 Issue 2 (pages 161-167) PMID: 21430872
  10. Imanishi J, Chan LWM, Broadhead ML, Pang G, Ngan SY, Slavin J, Sharp S, Choong PFM. Clinical Features of High-Grade Extremity and Trunk Sarcomas in Patients Aged 80 Years and Older: Why Are Outcomes Inferior? Front Surg. 2019 May 31;6:29. doi: 10.3389/fsurg.2019.00029. eCollection 2019. PubMed PMID: 31214596; PubMed Central PMCID: PMC6554445.
  11. Hoswell R, Broadhead ML, Tewari S. Bilateral neck of femur fractures in a paediatric patient with graves’ disease. J Paediatr Child Health. 2017 Jul;53(7):726-727. doi: 10.1111/jpc.13543. PubMed PMID: 28670805.
  12. Broadhead ML, Singla AA, Bertollo N, Broe D, Walsh WR. A Biomechanical Comparison of 4-Strand and 5-Strand Anterior Cruciate Ligament Graft Constructs. Orthop Rev (Pavia). 2017 Feb 21;9(1):6989. doi: 10.4081/or.2017.6989. eCollection 2017 Feb 20. PubMed PMID: 28286624; PubMed Central PMCID: PMC5337778.
  13. Thurairajah K, Broadhead ML, Balogh ZJ. Trauma and Stem Cells: Biology and Potential Therapeutic Implications. Int J Mol Sci. 2017 Mar 7;18(3). pii: E577. doi: 10.3390/ijms18030577. Review. PubMed PMID: 28272352; PubMed Central PMCID: PMC5372593.
  14. Imanishi J, Chan L, Broadhead ML, Ngan S, Slavin S, Pang G, Choong PFM. Clinical features of extremity or trunk sarcomas in patients aged 80 or older. Journal of Clinical Oncology 2016; 34 (15_supple), e22546-e22546.
  15. Broadhead ML, Lokmic Z, Tan ML, Stevenson A, Binns DS, Cullinane C, Hicks RJ, Choong PF, Myers DE. Applying Advanced Imaging Techniques to a Murine Model of Orthotopic Osteosarcoma. Front Surg. 2015 Aug 3;2:36. doi: 10.3389/fsurg.2015.00036. eCollection 2015. PubMed PMID: 26284252; PubMed Central PMCID: PMC4522961.
  16. Neptune DW, Estens JL, Kenny B, Broadhead ML. Pathological fracture of a giant cell tumour of the patella. Grand Rounds. 2014. 14: 6–10. doi: 10.1102/1470-5206.2014.0003
  17. Ghoz A, Broadhead ML, Morley J, Tavares S, McDonald D. Outcomes of dual modular cementless femoral stems in revision hip arthroplasty. Orthop Rev (Pavia). 2014 Mar 31;6(1):5247. doi: 10.4081/or.2014.5247. eCollection 2014 Jan 20. Review. PubMed PMID: 24822088; PubMed Central PMCID: PMC4017333.
  18. Broadhead ML, Lim HK, Ek ETH, Chia A. Multiple Femoral and Tibial Avulsion Fractures in a Skeletally Mature Patient Secondary to Knee Dislocation: A Case Report. JBJS Case Connect. 2013 Sep 11;3(3 Suppl 7):e89-e5. doi: 10.2106/JBJS.CC.L.00279. PubMed PMID: 29252270.
  19. Broadhead ML, Choong PF, Dass CR. Efficacy of continuously administered PEDF-derived synthetic peptides against osteosarcoma growth and metastasis. J Biomed Biotechnol. 2012;2012:230298. doi: 10.1155/2012/230298. Epub 2012 May 30. PubMed PMID: 22701300; PubMed Central PMCID: PMC3369529.
  20. Babazadeh S, Broadhead ML, Choong PF. If you are called to lead, you are called to serve. ANZ J Surg. 2011 Jun;81(6):401-3. PubMed PMID: 22295338.
  21. Broadhead ML, Babazadeh S, Ng KW, Choong PF, Stoney JD. Atraumatic bilateral femoral neck fractures during pregnancy: a missed diagnosis. Aust N Z J Obstet Gynaecol. 2011 Dec;51(6):563-4. doi: 10.1111/j.1479-828X.2011.01366.x. Epub 2011 Oct 10. PubMed PMID: 21981337.
  22. Broadhead ML, Dass CR, Choong PF. Systemically administered PEDF against primary and secondary tumours in a clinically relevant osteosarcoma model. Br J Cancer. 2011 Nov 8;105(10):1503-11. doi: 10.1038/bjc.2011.410. Epub 2011 Oct 6. PubMed PMID: 21979423; PubMed Central PMCID: PMC3242526.
  23. Babazadeh S, Broadhead ML, Schlicht SM, Powell GJ, Tymms GM. Pathologic fracture of a calcaneal aneurysmal bone cyst. J Foot Ankle Surg. 2011 Nov-Dec;50(6):727-32. doi: 10.1053/j.jfas.2011.04.036. Epub 2011 Jun 11. PubMed PMID: 21652227.
  24. Broadhead ML, Clark JC, Myers DE, Dass CR, Choong PF. The molecular pathogenesis of osteosarcoma: a review. Sarcoma. 2011:959248. doi: 10.1155/2011/959248. Epub 2011 Apr 13. PubMed PMID: 21559216; PubMed Central PMCID: PMC3087974.
  25. Broadhead ML, Clark JC, Dass CR, Choong PF, Myers DE. Therapeutic targeting of osteoclast function and pathways. Expert Opin Ther Targets. 2011 Feb;15(2):169-81. doi: 10.1517/14728222.2011.546351. Epub 2011 Jan 5. Review. PubMed PMID: 21204734.
  26. Broadhead ML, Babazadeh S, Goldwasser M, Choong PFM. Waxing and waning of joint motion. Grand Rounds. 2011. 11: 44-47. doi: 10.1102/1470-5206.2011.0011
  27. Broadhead ML, Babazadeh S, O’Brien B, Choong PF. Thigh enlargement and the art of misdirection. ANZ J Surg. 2010 Nov;80(11):839-40. PubMed PMID: 21033202.
  28. Broadhead ML, Clark JC, Dass CR, Choong PF. Microarray: an instrument for cancer surgeons of the future? ANZ J Surg. 2010 Jul Aug;80(7-8):531-6. doi: 10.1111/j.1445- 2197.2010.05379.x. Review. PubMed PMID: 20795968.
  29. Broadhead ML, Clark JC, Choong PF, Dass CR. Making gene therapy for osteosarcoma a reality. Expert Rev Anticancer Ther. 2010 Apr;10(4):477-80. doi: 10.1586/era.10.18. PubMed PMID: 20397911.
  30. Babazadeh S, Broadhead ML, Schlicht S, Slavin JL, Choong PFM. Giant cell tumour of metacarpal diaphysis. European Journal of Radiology 2010; 75(1):e31-e36.
  31. Broadhead ML, Akiyama T, Choong PF, Dass CR. The pathophysiological role of PEDF in bone diseases. Curr Mol Med. 2010 Apr;10(3):296-301. Review. PubMed PMID: 20236053.
    Broadhead ML, Becerra SP, Choong PF, Dass CR. The applied biochemistry of PEDF and implications for tissue homeostasis. Growth Factors. 2010 Aug;28(4):280-5. doi: 10.3109/08977191003604513. Review. PubMed PMID: 20166889; PubMed Central PMCID: PMC3931573.
  32. Dowsey MM, Broadhead ML, Stoney JD, Choong PF. Outcomes of total knee arthroplasty in English- versus non-English-speaking patients. J Orthop Surg (Hong Kong). 2009 Dec;17(3):305-9. PubMed PMID: 20065369.
  33. Broadhead ML, Dass CR, Choong PF. In vitro and in vivo biological activity of PEDF against a range of tumors. Expert Opin Ther Targets. 2009 Dec;13(12):1429-38. doi: 10.1517/14728220903307475. Review. PubMed PMID: 19922300.
  34. Babazadeh S, Broadhead ML, Slavin JL, Choong PF. An interesting diagnosis for a presacral mass: case report. Int Semin Surg Oncol. 2009 Nov 8;6:18. doi: 10.1186/1477-7800-6-18. PubMed PMID: 19895709; PubMed Central PMCID: PMC2777176.
  35. Broadhead ML, Dass CR, Choong PF. Cancer cell apoptotic pathways mediated by PEDF: prospects for therapy. Trends Mol Med. 2009 Oct;15(10):461-7. doi: 10.1016/j.molmed.2009.08.003. Epub 2009 Sep 25. Review. PubMed PMID: 19783213.

Text Books

  1. Broadhead ML, Sivaji S, Balogh ZJ, Choong PFM. Osteosarcoma pathogenesis: from molecular biology to mesenchymal stem cells. Osteosarcoma – Biology, Behavior and Mechanisms (2017), ISBN 978-953-51-4915-6.
  2. Open reduction and internal fixation of tibial plateau fractures. Robert Barbin, Sridhar Vijayan, Narlaka Jayasekara, Mathew J Alfredson. The tibial plateau fractures : diagnosis and treatment (volume 1); ISBN (Print): 978-1-68108-242-4 © 2016, Bentham eBooks imprint

Direct Anterior Approach 
Hip Replacement

Understanding the procedure, preparation and recovery. 


orthopaedic surgeon near me

©2024 Mid North Coast Hip & Knee Clinic | All Rights Reserved | Sitemap